Clinical Research Library
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B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review
Kennedy DO
2016
Vitamin D decreases adipocyte lipid storage and increases NAD-SIRT1 pathway in 3T3-L1 adipocytes
Eugene Chang Ph.D., Yangha Kim Ph.D.
2016
Long-term magnesium supplementation improves arterial stiffness in overweight and obese adults: results of a randomized, double-blind, placebo-controlled intervention trial.
Joris PJ, Plat J, Bakker SJ, Mensink RP
2016
Microcirculatory effects of zinc on fructose-fed hamsters.
Castiglione RC, Barros CM, Boa BC, Bouskela E
2016
L-carnitine prevents metabolic steatohepatitis in obese diabetic KK-Ay mice.
Kon K, Ikejima K, Morinaga M, Kusama H, Arai K, Aoyama T, Uchiyama A, Yamashina S, Watanabe S
2016
Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth.
Tarry-Adkins JL, Fernandez-Twinn DS, Hargreaves IP, Neergheen V, Aiken CE, Martin-Gronert MS, McConnell JM, Ozanne SE
2016
Antiproliferative effects of γ-tocotrienol are associated with lipid raft disruption in HER2-positive human breast cancer cells.
Alawin OA, Ahmed RA, Ibrahim BA, Briski KP, Sylvester PW
2016
Magnesium status and the metabolic syndrome: A systematic review and meta-analysis.
Sarrafzadegan N, Khosravi-Boroujeni H, Lotfizadeh M, Pourmogaddas A, Salehi-Abargouei A
2016
Circulating adiponectin concentrations are increased by dietary resistant starch and correlate with serum 25-hydroxycholecalciferol concentrations and kidney function in Zucker diabetic fatty rats.
Koh GY, Derscheid R, Fuller KN, Valentine RJ, Leow SE, Reed L, Wisecup E, Schalinske KL, Rowling MJ
2016
Coenzyme Q 10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth
Jane L Tarry-Adkins, Denise S Fernandez-Twinn, Iain P Hargreaves, Viruna Neergheen, Catherine E Aiken, Malgorzata S Martin-Gronert, Josie M McConnell, Susan E Ozanne
2016
High vitamin A intake during pregnancy modifies dopaminergic reward system and decreases preference for sucrose in Wistar rat offspring.
Sánchez-Hernández D, Poon AN, Kubant R, Kim H, Huot PS, Cho CE, Pannia E, Reza-López SA, Pausova Z, Bazinet RP, Anderson GH
2016
Selenium status and cardiovascular diseases: meta-analysis of prospective observational studies and randomized controlled trials.
Zhang X, Liu C, Guo J, Song Y
2016
Vitamin D Supplementation Affects the Beck Depression Inventory, Insulin Resistance, and Biomarkers of Oxidative Stress in Patients with Major Depressive Disorder: A Randomized, Controlled Clinical Trial.
Sepehrmanesh Z, Kolahdooz F, Abedi F, Mazroii N, Assarian A, Asemi Z, Esmaillzadeh A
2016
Association between Blood Omega-3 Index and Cognition in Typically Developing Dutch Adolescents.
van der Wurff IS, von Schacky C, Berge K, Zeegers MP, Kirschner PA, de Groot RH
2016
Association between Blood Omega-3 Index and Cognition in Typically Developing Dutch Adolescents
Inge S. M. van der Wurff, Clemens von Schacky, Kjetil Berge, Maurice P. Zeegers, Paul A. Kirschner, Renate H. M. de Groot
2016
L-Carnitine intake and high trimethylamine N-oxide plasma levels correlate with low aortic lesions in ApoE(-)(/-) transgenic mice expressing CETP.
Collins HL, Drazul-Schrader D, Sulpizio AC, Koster PD, Williamson Y, Adelman SJ, Owen K, Sanli T, Bellamine A
2016
Glutamine supplementation attenuates ethanol-induced disruption of apical junctional complexes in colonic epithelium and ameliorates gut barrier dysfunction and fatty liver in mice.
Chaudhry KK, Shukla PK, Mir H, Manda B, Gangwar R, Yadav N, McMullen M, Nagy LE, Rao R
2016
L-Carnitine intake and high trimethylamine N-oxide plasma levels correlate with low aortic lesions in ApoE / transgenic mice expressing CETP
Heidi L. Collins, Denise Drazul-Schrader, Anthony C. Sulpizio, Paul D. Koster, Yuping Williamson, Steven J. Adelman, Kevin Owen, Toran Sanli, Aouatef Bellamine
2016
Glutamine supplementation attenuates ethanol-induced disruption of apical junctional complexes in colonic epithelium and ameliorates gut barrier dysfunction and fatty liver in mice.
J Nutr Biochem
2016
Lymphocyte vitamin C levels as potential biomarker for progression of Parkinson's disease.
Ide K, Yamada H, Umegaki K, Mizuno K, Kawakami N, Hagiwara Y, Matsumoto M, Yoshida H, Kim K, Shiosaki E, Yokochi T, Harada K
2015
Lymphocyte vitamin C levels as potential biomarker for progression of Parkinson's disease
Ide K, Yamada H, Umegaki K, Mizuno K, Kawakami N, Hagiwara Y, Matsumoto M, Yoshida H, Kim K, Shiosaki E, Yokochi T, Harada K
2015
Functional cobalamin (vitamin B12) deficiency: role of advanced age and disorders associated with increased oxidative stress.
Solomon LR
2015
Vitamin D decreases adipocyte lipid storage and increases NAD-SIRT1 pathway in 3T3-L1 adipocytes.
Chang E, Kim Y
2015
Preventing Gut Leakiness and Endotoxemia Contributes to the Protective Effect of Zinc on Alcohol-Induced Steatohepatitis in Rats.
Zhong W, Li Q, Sun Q, Zhang W, Zhang J, Sun X, Yin X, Zhang X, Zhou Z
2015
Leptin and Adiponectin Modulate the Self-renewal of Normal Human Breast Epithelial Stem Cells.
Esper RM, Dame M, McClintock S, Holt PR, Dannenberg AJ, Wicha MS, Brenner DE
2015
Prediagnostic Plasma Adiponectin and Survival among Patients with Colorectal Cancer
Chong DQ, Mehta RS, Song M, Kedrin D, Meyerhardt JA, Ng K, Wu K, Fuchs CS, Giovannucci EL, Ogino S, Chan AT
2015
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio II, Giannopoulou EG, Rago C, Muley A, Asara JM, Paik J, Elemento O, Chen Z, Pappin DJ, Dow LE, Papadopoulos N, Gross SS, Cantley LC
2015
α-Tocopherol bioavailability is lower in adults with metabolic syndrome regardless of dairy fat co-ingestion: a randomized, double-blind, crossover trial.
Mah E, Sapper TN, Chitchumroonchokchai C, Failla ML, Schill KE, Clinton SK, Bobe G, Traber MG, Bruno RS
2015
Comparison of the effects of low-dose rosuvastatin on plasma levels of cholesterol and oxidized low-density lipoprotein in 3 ultracentrifugally separated low-density lipoprotein subfractions.
Homma K, Homma Y, Ozawa H, Shiina Y, Shibata T, Yoshida T, Hasegawa K, Kanda T, Tokuyama H, Wakino S, Hayashi K, Itoh H, Hori S
2015
Interaction between current vitamin D supplementation and menopausal hormone therapy use on breast cancer risk: evidence from the E3N cohort.
Cadeau C, Fournier A, Mesrine S, Clavel-Chapelon F, Fagherazzi G, Boutron-Ruault MC
2015
Prenatal choline and the development of schizophrenia
Freedman R, Ross RG
2015
Prenatal choline and the development of schizophrenia
Robert FREEDMAN, Randal G. ROSS
2015
Antioxidants can increase melanoma metastasis in mice.
Le Gal K, Ibrahim MX, Wiel C, Sayin VI, Akula MK, Karlsson C, Dalin MG, Akyürek LM, Lindahl P, Nilsson J, Bergo MO
2015
Omega-3 polyunsaturated fatty acid blood biomarkers increase linearly in men and women after tightly controlled intakes of 0.25, 0.5, and 1 g/d of EPA + DHA.
Patterson AC, Chalil A, Aristizabal Henao JJ, Streit IT, Stark KD
2015
Role of vitamin A in type 2 diabetes mellitus biology: effects of intervention therapy in a deficient state.
Iqbal S, Naseem I
2015
Selenium deficiency occurs in some patients with moderate-to-severe cirrhosis and can be corrected by administration of selenate but not selenomethionine: a randomized controlled trial.
Burk RF, Hill KE, Motley AK, Byrne DW, Norsworthy BK
2015
Low serum magnesium is associated with coronary artery calcification in a Korean population at low risk for cardiovascular disease.
Lee SY, Hyun YY, Lee KB, Kim H
2015
Gestational marginal zinc deficiency impaired fetal neural progenitor cell proliferation by disrupting the ERK1/2 signaling pathway.
Nuttall JR, Supasai S, Kha J, Vaeth BM, Mackenzie GG, Adamo AM, Oteiza PI
2015
Microarray analysis of pancreatic gene expression during biotin repletion in biotin-deficient rats.
Dakshinamurti K, Bagchi RA, Abrenica B, Czubryt MP
2015
Vitamin D and Dysfunctional Adipose Tissue in Obesity
Stokić E, Kupusinac A, Tomic-Naglic D, Smiljenic D, Kovacev-Zavisic B, Srdic-Galic B, Soskic S, Isenovic ER
2015
L-Carnitine supplementation improved clinical status without changing oxidative stress and lipid profile in women with knee osteoarthritis.
Malek Mahdavi A, Mahdavi R, Kolahi S, Zemestani M, Vatankhah AM
2015
Vitamin A exerts its antiinflammatory activities in colitis through preservation of mitochondrial activity.
Reifen R, Levy E, Berkovich Z, Tirosh O
2015
Effects of Oral Vitamin C Supplementation on Anxiety in Students: A Double-Blind, Randomized, Placebo-Controlled Trial.
de Oliveira IJ, de Souza VV, Motta V, Da-Silva SL
2015
The effect of vitamin K1 supplementation on sensitivity and insulin resistance via osteocalcin in prediabetic women: a double-blind randomized controlled clinical trial.
Rasekhi H, Karandish M, Jalali MT, Mohammad-Shahi M, Zarei M, Saki A, Shahbazian H
2015
Oral N-acetylcysteine reduces plasma homocysteine concentrations regardless of lipid or smoking status.
Hildebrandt W, Sauer R, Bonaterra G, Dugi KA, Edler L, Kinscherf R
2015
Thiamine and magnesium deficiencies: keys to disease.
Lonsdale D.
2015
Biomarkers of Nutrition for Development— Folate Review
Lynn B Bailey, Patrick J Stover, Helene McNulty, Michael F Fenech, Jesse F Gregory III, James L Mills, Marie A Caudill, Barry Shane, Ramkripa Raghavan, Christine M Pfeiffer, Daniel J Raiten, Robert J Berry, Regan L Bailey, Zia Fazili, Mindy Zhang, Per M Ueland, Dorothy B Hausman, Anne M Molloy
2015
Effects of Testosterone Administration for 3 Years on Subclinical Atherosclerosis Progression in Older Men With Low or Low-Normal Testosterone Levels: A Randomized Clinical Trial.
Basaria S, Harman SM, Travison TG, Hodis H, Tsitouras P, Budoff M, Pencina KM, Vita J, Dzekov C, Mazer NA, Coviello AD, Knapp PE, Hally K, Pinjic E, Yan M, Storer TW, Bhasin S
2015
High-density lipoprotein cholesterol, a protective or a risk factor for developing coronary heart disease? Tehran Lipid and Glucose Study.
Hashemi Nazari SS, Shakiba M, Khalili D, Hadaegh F, Tohidi M, Azizi F
2015
Randomized, double-blind, placebo-controlled pilot trial of reduced coenzyme Q10 for Parkinson's disease.
Yoritaka A, Kawajiri S, Yamamoto Y, Nakahara T, Ando M, Hashimoto K, Nagase M, Saito Y, Hattori N
2015
Real-time cell analysis of the inhibitory effect of vitamin K2 on adhesion and proliferation of breast cancer cells.
Kiely M, Hodgins SJ, Merrigan BA, Tormey S, Kiely PA, O'Connor EM
2015
Effects of selenium supplementation on glucose homeostasis, inflammation, and oxidative stress in gestational diabetes: Randomized, double-blind, placebo-controlled trial.
Asemi Z, Jamilian M, Mesdaghinia E, Esmaillzadeh A
2015
Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
Rios-Avila L, Coats B, Ralat M, Chi YY, Midttun Ø, Ueland PM, Stacpoole PW, Gregory JF
2015
Oxidized low-density lipoprotein is a common risk factor for cardiovascular diseases and gastroenterological cancers via epigenomical regulation of microRNA-210
Ku-Chung Chen, Yi-Chu Liao, Jaw-Yuan Wang, Ying-Chu Lin, Chung-Ho Chen, Suh-Hang H. Juo
2015
Myo-inositol Supplementation for Prevention of Gestational Diabetes in Obese Pregnant Women: A Randomized Controlled Trial.
DAnna R, Di Benedetto A, Scilipoti A, Santamaria A, Interdonato ML, Petrella E, Neri I, Pintaudi B, Corrado F, Facchinetti F
2015
Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
Saboori S, Shab-Bidar S, Speakman JR, Yousefi Rad E, Djafarian K
2015
Oxidized low-density lipoprotein is a common risk factor for cardiovascular diseases and gastroenterological cancers via epigenomical regulation of microRNA-210.
Chen KC, Liao YC, Wang JY, Lin YC, Chen CH, Juo SH
2015
Dietary cholesterol and cardiovascular disease: a systematic review and meta-analysis.
Berger S, Raman G, Vishwanathan R, Jacques PF, Johnson EJ
2015
Association of Insulin Resistance With Cerebral Glucose Uptake in Late Middle-Aged Adults at Risk for Alzheimer Disease.
Willette AA, Bendlin BB, Starks EJ, Birdsill AC, Johnson SC, Christian BT, Okonkwo OC, La Rue A, Hermann BP, Koscik RL, Jonaitis EM, Sager MA, Asthana S
2015
Vitamin K1 alleviates streptozotocin-induced type 1 diabetes by mitigating free radical stress, as well as inhibiting NF-κB activation and iNOS expression in rat pancreas.
Varsha MK, Thiagarajan R, Manikandan R, Dhanasekaran G
2015
Efficacy and safety of an amino acid jelly containing coenzyme Q10 and L-carnitine in controlling fatigue in breast cancer patients receiving chemotherapy: a multi-institutional, randomized, exploratory trial (JORTC-CAM01).
Iwase S, Kawaguchi T, Yotsumoto D, Doi T, Miyara K, Odagiri H, Kitamura K, Ariyoshi K, Miyaji T, Ishiki H, Inoue K, Tsutsumi C, Sagara Y, Yamaguchi T
2015
Magnesium supplementation affects metabolic status and pregnancy outcomes in gestational diabetes: a randomized, double-blind, placebo-controlled trial.
Asemi Z, Karamali M, Jamilian M, Foroozanfard F, Bahmani F, Heidarzadeh Z, Benisi-Kohansal S, Surkan PJ, Esmaillzadeh A
2015
Vitamin E has a beneficial effect on nonalcoholic fatty liver disease: A meta-analysis of randomized controlled trials.
Sato K, Gosho M, Yamamoto T, Kobayashi Y, Ishii N, Ohashi T, Nakade Y, Ito K, Fukuzawa Y, Yoneda M
2015
Retinoic Acid Differentially Regulates the Migration of Innate Lymphoid Cell Subsets to the Gut.
Kim MH, Taparowsky EJ, Kim CH
2015
Effect of the Probiotic Saccharomyces boulardii on Cholesterol and Lipoprotein Particles in Hypercholesterolemic Adults: A Single-Arm, Open-Label Pilot Study.
Ryan JJ, Hanes DA, Schafer MB, Mikolai J, Zwickey H
2015
Vitamin D3 seems more appropriate than D2 to sustain adequate levels of 25OHD: a pharmacokinetic approach.
Oliveri B, Mastaglia SR, Brito GM, Seijo M, Keller GA, Somoza J, Diez RA, Di Girolamo G
2015
Change in psychiatric symptomatology after benfotiamine treatment in males is related to lifetime alcoholism severity.
Manzardo AM, Pendleton T, Poje A, Penick EC, Butler MG
2015
The effects of folic acid on global DNA methylation and colonosphere formation in colon cancer cell lines.
Farias N, Ho N, Butler S, Delaney L, Morrison J, Shahrzad S, Coomber BL
2015
The effects of folic acid on global DNA methylation and colonosphere formation in colon cancer cell lines
Nathan Farias, Nelson Ho, Stacey Butler, Leanne Delaney, Siranoush Shahrzad, Brenda L. Coomber, Jodi Morrison
2015
Blood Telomere Length Attrition and Cancer Development in the Normative Aging Study Cohort
Lifang Hou, Brian Thomas Joyce, Tao Gao, Lei Liu, Yinan Zheng, Frank J. Penedo, Siran Liu, Wei Zhang, Raymond Bergan, Dai Qi, Pantel Vokonas, Mirjam Hoxha, Joel Schwartz, Andrea Baccarelli
2015
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