Can High Dose Vitamin E Reduce Kidney Inflammation?

Published on
January 30, 2017

A recently published study in the Journal of Clinical Lipidology suggests a possible relationship. In this randomized double-blind placebo-controlled trial (the gold standard for medical publications), sixty diabetics with confirmed kidney disease were divided into two groups:  one group (n=30) took 1200 IU/d of vitamin E, while the other group (n=30) took placebo. After 12 weeks, the group taking vitamin E showed a significant reduction in several biomarkers of kidney  inflammation; although glucose levels and insulin resistance (biomarkers for blood sugar control and indicators of developing diabetes) showed no improvement, there was a significant decrease in insulin concentration (a positive biological effect).

For more details, download our abstract entitled The effects of high-dose vitamin E supplementation on biomarkers of kidney injury, inflammation, and oxidative stress in patients with diabetic nephropathy: A randomized, double-blind, placebo-controlled trial.